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Am I a candidate for MammoSite 5-Day Targeted Radiation Therapy?

Four medical societies have created guidelines to help doctors select patients who can benefit from MammoSite 5-Day Targeted Radiation Therapy.

Professional Medical Society Consensus Guidelines:
Patient Selection Criteria for Accelerated Partial Breast Irradiation
  ABS1 ASBS2 ACRO3 ASTRO4
Suitable Cautionary
Age ≥50 ≥45 ≥45 ≥60 50-59
Diagnosis Unifocal, invasive ductal carcinoma Invasive ductal carcinoma or ductal carcinoma in situ (DCIS) Invasive ductal carcinoma or DCIS Invasive ductal or other favorable subtypes (ie: mucinous, tubular, colloid) Pure DCIS ≤3cm EIC ≤3cm
Tumor Size ≤3cm ≤3cm ≤3cm ≤2cm 2.1-3.0cm
Surgical Margins Negative microscopic margins of excision Negative microscopic surgical margins of excision Negative microscopic surgical margins of excision Negative by at least 2mm Close (<2mm)
Nodal Status NØ (i-,i+)  

1M.Keisch, et al. Breast Brachytherapy Task Group, American Brachytherapy Society. February, 2007. http://www.Americanbrachytherapy.org
2Consensus statement for accelerated partial breast irradiation. The American Society of Breast Surgeons. December 8, 2005.
3American College of Radiation Oncology Statement on Partial Breast Irradiation. September, 2008.
4American Society for Radiation Oncology Consensus Statement on Partial Breast Irradiation. July 2009.

Dr. Alison Laidley, breast surgeon, describes the patient selection criteria for MammoSite 5-Day Targeted Radiation Therapy.9,10,11,12

MammoSite Targeted Radiation Therapy: Adobe Flash Player

Video Transcript: The patient selection criteria are available on the website of the American Society of Breast Surgeons as well as the American Brachytherapy Society.

But in general the patient needs to be a candidate for breast conservation. Meaning a small tumor less than three centimeters with clean margins, that’s called negative margins, in other words there is no cancer on the margins that after the lumpectomy, greater than 45 years of age and lymph node negative.

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